Which layer of the small intestine has the best holding power for anastomosis?

The submucosa is the most appropriate layer of the small intestine to consider for anastomosis due to its structural properties and composition. This layer contains a dense network of connective tissues, blood vessels, lymphatics, and nerves, which provide the necessary support and stability. Its thickness and strength help ensure that the sutures or staples used in the anastomosis can hold firmly, facilitating proper healing and minimizing the risk of dehiscence (reopening of the surgical site).

In the context of surgical procedures, the integrity and strength of the anastomosis are crucial for successful outcomes. The submucosa, being well-vascularized, also contributes positively to tissue healing and nutrient supply, which are vital for recovery following an intestinal resection. The other layers, while they have important functions, do not possess the same combination of strength and supportive features, making the submucosa the best choice for secure anastomosis in the small intestine.