What type of infiltrate would be expected with immune-mediated arthritis?

In the context of immune-mediated arthritis, the type of infiltrate that is most likely to be expected is a lymphocytic infiltrate. Immune-mediated arthritis primarily involves an inappropriate immune response directed against the synovial tissue, leading to inflammation. This type of arthritis is typically characterized by the presence of lymphocytes, which are a key component of the adaptive immune response.

Lymphocytes, including T cells and B cells, play a crucial role in mediating immune responses. Their infiltration into the joint tissue reflects the underlying immunological processes at play in conditions such as rheumatoid arthritis or other autoimmune forms of inflammatory arthritis.

While neutrophils may be involved in acute inflammation, they are more typically associated with infectious processes rather than the chronic inflammation seen in immune-mediated arthritis. Monocytes, which can differentiate into macrophages, may also be present but are not the primary cell type associated with the immune-mediated process. Eosinophils primarily respond to allergic reactions and parasitic infections, and their infiltrate would not be indicative of immune-mediated arthritis.

Focusing on lymphocytic infiltrate aligns with the pathophysiology of the disease, emphasizing chronic inflammation driven by the immune response rather than infection or allergies. This insight is essential for