What is the reversal agent for oxymorphone?

The reversal agent for oxymorphone is naloxone. Oxymorphone is an opioid analgesic, and naloxone is specifically designed to counteract the effects of opioids by competitively binding to opioid receptors in the central nervous system. When administered, naloxone displaces opioids at these receptors, thus reversing the analgesic effects, respiratory depression, and sedation associated with opioid overdose. This makes naloxone a critical medication in situations where quick reversal of opioid effects is necessary, such as in cases of overdose or adverse reactions to opioid medications.

Other agents listed serve different purposes; for instance, flumazenil is a benzodiazepine antagonist and does not affect opioid receptor activity. Atipamezole is used for reversing alpha-2 adrenergic agonists, which are not related to opioids, while yohimbine also functions as an alpha-2 antagonist but does not work on opioid receptors. Thus, naloxone is the appropriate choice for reversing the effects of oxymorphone specifically.